Central Cemento-Ossifying Fibroma in the Mandible. Case report.

Abstract

Central Cemento-Ossifying Fibroma (CCOF) is a benign fibro-osseous neoplasm of mesodermal origin, specifically from multipotent cells of the periodontal ligament and bone tissue, differentiating into cementum-like mineralized tissue within its structure. Clinically, it presents as a volume increase, causing expansion of the cortical bones and thickening of adjacent structures, leading to a noticeable deformity. It is asymptomatic, firm, and has a slow progression. It mainly affects patients in their third and fourth decades of life, with a higher prevalence in females. The most common location is the posterior mandibular region. Objective: This research study aims to present a case, revealing the clinical, histopathological, prognostic aspects, and surgical treatment of this pathology. Case Report: The patient is a 42-year-old female who exhibited a volume increase in the mandibular region, predominantly on the right side, with a 5-year progression. She had previously consulted another physician who performed an incisional biopsy, which was sent for histopathological study, diagnosing Central Cemento-Ossifying Fibroma (CCOF). She was referred to our service for evaluation and treatment. Results and Conclusions: The treatment of choice was a bilateral block resection involving the left mandibular angle, using pre-designed cutting guides to obtain 1cm safety margins on each side of the lesion. Six months later, the patient showed good results and successful evolution. She is currently in planning for reconstruction with a microvascularized graft and rehabilitation.