Autoimmune Thyroid Disease and its characterization in the Endocrinology Department of the CMDLT

Abstract

Autoimmune thyroid diseases (ATE) are produced by changes in immunological tolerance; includes hypothyroidism and hyperthyroidism; Likewise, subclinical thyroid dysfunction can be related to ATS in the initial phases, such as dyslipidemia, cardiovascular disease and metabolic alterations, thus the need to characterize it arises.This is an observational, descriptive, cross-sectional and retrospective study; included 101 patients with ATS, thyroid echo, lipids, and thyroid hormones, excluding those who were taking drugs that modify thyroid hormones. Cardiovascular risk (CVR) was established using WHO/ISH CVR AMR B and Framingham. 92% of the patients were female and 8% male; average age 43.9 years; 92.08% had hypothyroidism, 7.92% with hyperthyroidism and 25% subclinical hypothyroidism, of which 37% were overweight and 27% obese; 10.89% diabetes mellitus (DM) and 11.88% prediabetes; 51.49% hypercholesterolemia. 57.43% low CVR. The presence of DM, prediabetes, hypercholesterolemia, hypertriglyceridemia, and elevated LDL were correlated with ATE (P: 0.65; P: 0.82; p: 0.72; p: 0.77 and p: 0.87). ETA is one that is more common in women, which coincides with the results obtained. Overweight and obesity were identified in most of them as factors that trigger ATS. The relationship between DM and ATS is controversial; no significant relationship was found in the study either. ETA has not been associated with CVR, but it has been associated with dyslipidemia. ETA is an autoimmune pathology, predominates in young women; it is associated with dyslipidemia, overweight and obesity; as soon as DM or prediabetes and CVR is recommended to continue its study.