Intravenous lidocaine effect over propofol consumption in patients sedation undergoing colonoscopy

Intravenous lidocaine effect

Abstract

Sedation is a technique that aims to relieve anxiety, avoid discomfort or pain and hypnosis of patients during colonoscopic procedures. Propofol has become the first sedative drug of choice for colonoscopy due to its rapid action, short half-life, and rapid recovery. However, respiratory depression, cardiovascular events have been the common complications related to this drug. Intravenous infusion of lidocaine is safe and has advantages such as reducing the need for other anesthetics, so it can reduce propofol requirements during these procedures. Objective: to evaluate the effect of intravenous lidocaine on the consumption of propofol in sedation of patients undergoing colonoscopic procedures. Materials and methods: experimental study type Clinical Trial, randomized, single blind. Sample: 40 patients distributed in two groups of 20 taken randomly, who underwent colonoscopic procedures; during the period between August 2022 and October 2022. Conclusions: the study demonstrated that the addition of lidocaine to propofol in sedation to perform colonoscopic procedures had as results; First, intravenous lidocaine reduced the time and consumption of propofol from infusion to loss of consciousness with a P (0.038), Second, the total dose of propofol used decreased in the group to which lidocaine was added with P (0.001). Third, there was no evidence of significant side effects related to the addition of lidocaine.