Endometrial biopsy: Comparison between the sample obtained by hysteroscopy and that obtained with pipelle cannula

Abstract

Introduction: Endometrial biopsy is used to evaluate the endometrial cavity, for hormonal evaluation of the endometrium and in the preoperative hysterectomy for benign lesions, for investigation of occult endometrial cancer. Hysteroscopy and aspiration with Pipelle are the two most commonly used methods today. Objective: To evaluate the diagnostic performance of endometrial biopsy taken with Pipelle cannula taken and taken by hysteroscopy to a group of patients who attended the minimally invasive gynecology consultation of CMDLT. Results: The mean age of the patients was 43.77 ± 6.63 years. 25 (83.3 %) and 27 (90 %) of the biopsies taken with hysteroscopy and Pipelle, respectively, were satisfactory (p = 0.250). The gland/stroma ratio was ≤ to 1:1 in 83.3 % and 53.3 % respectively (p < 0.001). The diagnostic agreement between both samples was 86.7 %. A sensitivity of 71.4% and specificity of 100% were obtained for the Pipelle, with respect to hysteroscopic biopsy. Both procedures were well tolerated, there was only one case of vasovagal reaction with Piperelle biopsy. Conclusions: The diagnostic yield of the biopsy taken with Pipelle, considering hysteroscopy as a reference standard, was high.