Krukenberg tumor: about a clinical case

Abstract

Krukenberg tumor represents between 5% and 30% of metastatic ovarian tumors, the main locations of metastasis to the ovary were of gastric origin (67%), followed by colon and rectum (9%), breast (7%), gallbladder and bile duct. Krukenberg tumor is defined as an adenocarcinoma metastatic to the ovary that contains mucin-producing signet ring cells. Adenocarcinomas with signet ring cells are 4 times more associated with ovarian metastases than any other malignancy; it generally occurs in the fifth decade of their lives with an average age of 45 years, The pathogenesis of Krukenberg tumor is an example of the selective spread of carcinomas, in this case, in the gastro-ovarian axis, this axis of tumor spread has attracted attention , especially when gastric neoplasms were found to selectively metastasize to the ovaries, there is several evidence supporting retrograde lymphatic spread as the most likely route.